Changes to the network interface and a small processor revision sound minor but could make a difference for your project.
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Raspberry Pi 3 Model B+ Review
Use this Raspberry Pi 3 Model B Motherboard when building your own custom computer. The circuit board comes with on-board 802.11N wireless LAN and Bluetooth 4.0 connectivity capabilities. It features a quad-core 64-bit ARM Cortex A53 clocked at 1.2 GHz. To get started you'll need to buy a Micro SD card with NOOBS and Micro USB power supply, sold separately. To use the computer motherboard to build a desktop computer you'll need a monitor or TV with HDMI cable, keyboard and mouse.
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